BIO, NANO & NEUROTECH

“Stories about aging have traditionally focused on the need for graceful accommodation. The recommended solution to diminishing vigor and impending death was resignation coupled with an effort to achieve closure in practical affairs and personal relationships. Given that nothing could be done to prevent or retard aging, this focus made sense. Rather than fretting about the inevitable, one could aim for peace of mind. Today we face a different situation. While we still lack effective and acceptable means for slowing the aging process, we can identify research directions that might lead to the development of such means in the foreseeable future. “Deathist” stories and ideologies, which counsel passive acceptance, are no longer harmless sources of consolation. They are fatal barriers to urgently needed action.” Nick Bostrom

Longevity

Longevity FAQ - Nintil. Covers major longevity concepts and misconceptions.
Fight Aging FAQ - Reason. Covers major longevity concepts and misconceptions.
Longevity FAQ - Laura Deming. Covers main longevity concepts and misconceptions.
Longevity Technology - Aaron King. An overview of the state of the art and major challenges in longevity.
How to Cure Aging, What Are You Doing With Your Life? - Kurzgesagt. Explainer videos on aging.
Your Life in Weeks, You’re at the tail end of your life - Tim Urban. Post that breaks down a human life into weeks, and breaks down time remaining into chunks of experiences to be had.
Transhumanism and Healthy Life Extension, The Million Year Lifespan - Reason. On ambitious plans for human health extension.
It Is Time To Classify Biological Aging as a Disease - NCBI. On the benefits of classifying aging as a disease, especially for FDA approval of aging drugs.
A Systematized Roadmap for the Longevity Industry - Biogerontology Research Foundation.
Biotech & Healthextension Focus - Foresight Institute. Recordings and seminar summaries of monthly seminars on longevity research, companies, funding.
A Reimagined Research Strategy for Aging - SENS. Dated but still considered a good overview of main aging areas to solve.
How to Start a Biotech Company in the Longevity Industry - Reason. Practical advice for entrepreneurs in the longevity space.
A Nuanced Opposition to the FDA - Reason. Why the current FDA drug approval process is a major roadblock on advancing longevity progress.
100 Plus - How The Coming Age of Longevity will change everything - Sonia Arrison. Thematic overview of how major areas in our lives will be changed with increased healthspans.
AI in Life-Extension: From Deep Learning to Superintelligence - Mikhail Batin et al. From near-term benefits of AI for longevity to potential futuristic implications of AI for longevity.
Michael Lustgarten, BluePrint, SlowMyAge, Howisfelix.today - Personal longevity tracking and improvement blogs.
Senescence.info - Website. Overview of the longevity field.
Lifespan.io - Website. Explainers, news, roadmaps, and other resources.
Creon’s Life Extension References - Creon Levit. Link list on life extension and diet.

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Cryonics

Why Cryonics Makes Sense - Tim Urban. A primer on why it makes sense to sign up to cryonics.
Cryonics - Reason. A brief explainer on the main concepts and controversies in cryonics.
Cryostasis Revival - Robert Freitas. Book about nanomedicine for revival.
Cryonics: Alcor FAQ - Alcor. An FAQ about cryonics, and about the practices of the provider Alcor.
Alcor vs. Cryonics Institute - Lesswrong. A comparison of Alcor versus the Cryonics Institute as providers for cryonics services. Now there is also TomorrowBiostasis, a European Cryonics Company.
Cryonics Q&A & Sign-up - Foresight Institute. A sign-up tutorial with Alcor and TomorrowBiostasis.

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Biotech

Benefits & Risks of Biotechnology - FLI. Introductory post with link list.
Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves - George Church. An optimistic outlook into biotechnology’s promises by one of the pioneers of the field.
Liberation Biology: The Scientific and Moral Case for the Biotech Revolution - Ronald Bailey. A moral argument in favor of advancing biotechnology.
Life As It Could Be: Astrobiology, Synthetic Biology, and the Future of Life - Library of Congress. A longish but interesting live stream of a synbio conference giving a good overview of the state of the art in the field.
CRISPR - Kurzgesagt. Illustrative explainer video on CRISPR and designer babies.

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Nanotech

Tiny Machines - Richard Feynman. Introducing the concept of nanotechnology.
About Nano, Molecular Machines Group, Technical Competitions on Molecular Machines, Deployment and Development of Nanomaterials and Nanomedicine - Foresight Institute. Various explainers and technology reviews of nanotechnology.
Bottleneck Analysis: Positional Chemistry - Adam Marblestone. Workshop summary that provides a good overview of state of the art and open challenges.
Protein-based Assemblies and Molecular Machines - David Baker. Current state of the art in molecular machines.
Introduction to CadNano - Shawn Douglas, UCSF. Current state of the art in software for molecular machines.
In-silico design, Visualization, and Analysis of Large DNA and RNA Nanostructures- Erik Poppleton, oxDNA. Current state of the art in software for molecular machines.
The Science Behind Fold-It - Website. Current state of the art in software for molecular machines.
Nanotechnology: Molecular Machinery, Manufacturing, and Computation - Eric Drexler. Technical book explaining the fundamentals and implications of nanotechnology.
Drexler and Smalley make the case for and against nanotechnology - Rudy Baum. Summarizes the Drexler Smalley debate about molecular manufacturing.

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Neurotech

TheNeurotech - Website. An overview of the neurotechnology domain.
Neurotech Group - Foresight Institute. Application-based seminar group with recordings published on Youtube.
Lessons - Website. A step-by-step guide into BCIs.
BCI community - Website. Link list for BCI explainers and labs.
Mind-uploading - Kurzgesagt. Explainer video on mind-uploading.
Roadmap to WBE - Anders Sandberg, Nick Bostrom. Oldie but goldie on steps required toward Whole Brain Emulation.
Whole Brain Emulation - LessWrong. A primer on Whole Brain Emulations.
Minduploading.org - FAQ and articles on mind-uploading.
Digital People FAQ - Holden Karnofsky. An FAQ that includes societal questions.
Neuralink: The Brain’s Magical Future - Tim Urban. An overview of Neuralink’s likely plans for Brain Computer Interfaces.
Challenges for Brain Emulation- Alice Parker, Rick Cattell. Focuses on the technical challenges for building brain emulations.
A Taxonomy and Metaphysics of Mind-Uploading - Keith Wiley. Detailed book on the foundations for mind-uploading with multiple helpful illustrations.
Mind-Uploading - A Philosophical Analysis - David Chalmers. A philosophical exploration of questions regarding the consciousness of mind-uploads.
Intelligence: Human, AI, Hybrids - Randal Koene, David Eagleman, Robert McIntyre, Nell Watson. Foresight Vision Weekend panel on potential future mind architectures.
Coalescing Minds: Group mind-related Uploading Scenarios- Kaj Sotjala. On the possibility of group minds emerging from WBEs.
From Brain Preservation to Reconstruction - Carboncopies’ workshop videos.
Engineering Serendipity: Solving Scientific Problems in the 21st Century - Ed Boyden. Near-term progress in neurotechnology and mapping the brain.

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Biotech

Biosecurity - EA Forum. Landing page to EA’s biosecurity section with intro to the topic and a list of links, such as A Biosecurity and Biorisk Reading List - Tessa Alexanian.
Existential Risk and Cost-effective Biosecurity - Piers Millett and Andrew Snyder-Beattie. Focuses on addressing risks from bioweapons.
Insidious Insights: Implications of Viral Vector Engineering for Pathogen Enhancement - Jonas Sandbrink et al. On dual-use insights relevant to the enhancement of pandemic pathogens.
Engineering the Apocalypse, Recipes for Future Plagues - Rob Reid, Sam Harris. Podcast episodes with transcripts on biosecurity and pandemics.

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Nanotech

Atomically Precise Manufacturing - EA Forum. Landing page to EA’s APM section with intro to the topic and a list of links.
Risks from Atomically Precise Manufacturing - Benjamin Hilton. On risks and benefits of APM and potential avenues for addressing the risks.
My Thoughts on Nanotechnology Strategy as EA Cause Area - Ben Snoding. On whether and how Nanotechnology should feature as an effective altruist cause area.
Nanotechnology Catastrophic Risk Map - Alexey Turchin. Visual map of various X-risk scenarios from Nanotechnology.
Evaluating Future Nanotechnology: The Net Social Impacts of APM - Seth Baum. Weighing risks and benefits from future molecular nanotechnology.
Nano Policy Briefings - Foresight Institute. On risks and policy advice regarding nanotechnology.

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Neurotech

Ethics of Brain Emulations, Is Brain Emulation Dangerous? - Anders Sandberg, Peter Eckersley. Discusses ethical challenges around WBEs.
Criticisms of WBE - David Matthewman. Discusses risks associated with WBEs.
Could we Use Untrustworthy WBE’s to Make Trustworthy Ones? - Carl Schulman. Focuses on safety and security considerations of WBEs.
A New X-Risk Factor: Brain Computer Interfaces - Jack. On potentially catastrophic implications of BCIs regarding totalitarianism and information security.
Sharing the World With Digital Minds - Nick Bostrom, Carl Schulman. On how current human intuitions are insufficient for living in a world with digital minds.
Cognitive Enhancement: Methods, Ethics, Regulatory Challenges - Anders Sandberg, Nick Bostrom. A primer on the main societal challenges around cognitive enhancement.‍
Cause Area: Differential Neurotechnology Development - EA Forum. Argues that neurotechnology is significantly undervalued as EA cause area given its potential implications and opportunities for differential technology development.

Longevity

The Fable of the Dragon Tyrant - Nick Bostrom. Much-cherished fairy-tale-like story illustrating the loss incurred by aging and our deathist acceptance.
Childhood’s End - Arthur C. Clarke. Fictional account of the end of death.
San Junipero - BlackMirror. About a love story in the afterlife.
Death & Anti-Death Series - Charles Tandy. Dated but contains various optimistic longevity-focused contributions.
Altered Carbon - TV series. Not always positive.
In Time - Movie. A society in which people stop aging.
Longevity Tree 1, Longevity Tree 2, Biotech Tree - Foresight Institute. Technology trees to reach escape velocity in longevity.

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Biotech

The Hedonistic Imperative - David Pearce. A manifesto-like book on the benefits of biotech, neurotech, and similar technologies to enable humans escape our hedonic treadmill.
The Transhumanist Reader - Natasha Vita-More, Max More. A now dated book with various chapter contributions by major transhumanist writers.
Crazy Ides for Future Synbio & Bioengineering - Stephen Malina. Lists potential future goals and applications in biotechnology.

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Nanotech

Nexus - Ramez Naam. On a nano drug that allows mind-melding.
Diamond Age - Neal Stephenson. A girl adventuring in a nanotechnology-defined future.
Radical Abundance, Engines of Creation, Nano-solutions for the 21st Century - Eric Drexler. Various nanotechnology-focused books that inspired much early work on nanotechnology.
What Does The Future Hold For Molecular Machines? | James Cooper, Nanotechnology Roadmap, Nanotech Tree 1, Nanotechtree 2 - Foresight Institute. Concepts and technology trees to advance toward atomically precise manufacturing.
Nanotechnology’s Spring - Eli Dourado. Easy-to-digest intro to the early promises of nanotechnology and recently accelerating progress.

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Neurotech

Age of Em, Is Forgotten Party Death? - Robin Hanson. On the economics of a world populated by human-brain emulations.
What Brain Computer Interfaces Could Mean for the Future of Work - Alexandre Gonfalonieri. A business-focused outlook of the potential of BCIs.
BestHope - Future Strategist. BCI-focused podcast episode.
Permutation City - Greg Egan. On long-term dynamics in a human upload-defined future.
Fun Theory - Eliezer Yudkowsky. On why a future defined by advanced neurotechnology does not have to be boring.
The Ultimate Interface: Your Brain - Ramez Naam. On the promises of brain machine interfaces.
Embodiment in Whole Brain Emulation and it’s Implications for Death Anxiety - Charl Linssen, Pieter Lemmens. Explores implications of WBEs for overcoming existential angst.
Whole Brain Emulation as Platform for AGI Safety - Anna Salamon, Carl Schulman. Focuses on AI safety implications of WBEs.‍
Neurotech Tree - Foresight Institute. Technology tree toward BCIs.

Longevity

FightAging has an extensive list of funds, nonprofits and blogs of interest listed on the right-handside and is itself a great resource.
Agingbiotechinfo - Karl Pfleger. Covers companies, conferences, diagnostics, resources, and more.
Longevity List - Nathan Cheng. Newsletter and list on major longevity companies.
Longevity Prize - VitaDAO & Foresight Institute. Awarding outstanding progress in longevity research — crowdsourced and curated by leading industry experts.

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Biotech

Cambridge Working Group - “Works to address the risks of Potential Pandemic Pathogen research through promoting public understanding, risk assessment and regulation of such research.
Biomedical Advanced Research and Development Authority (BARDA) - Develops and procures needed medical countermeasures (MCMs), including vaccines, therapeutics, diagnostics, and non-pharmaceutical countermeasures, against a broad array of public health emergencies in the US.

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Nanotech

Foresight Institute - Supports the beneficial development of high-impact technologies to make great futures more likely.
Institute for Molecular Manufacturing - Conducting and catalyzing research on Atomically Precise Manufacturing.
Zyvex Labs - Developing ‘Atomically Precise Manufacturing’ to create society-changing devices—devices in which control of the location of individual atoms at the single-lattice-site level yields unprecedented capabilities.

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Neurotech

Nectome - Our mission is to preserve your brain well enough to keep all its memories intact.
Brain Preservation Foundation - A nonprofit research organization with the mission to promote scientific research and services development of whole brain preservation for long-term static storage.
Kernel - At Kernel, our primary aim is to develop technologies to understand and treat neurological diseases in new and exciting ways.
Neuralink - Neuralink is developing ultra-high bandwidth brain-machine interfaces to connect humans and computers.
Carboncopies - Promoting R&D for Whole Brain Emulations.
BRAIN Initiative - Produce a new dynamic picture of the brain that, for the first time, shows how individual cells and complex neural circuits interact.
Human Connectome Project - Aims to provide an unparalleled compilation of neural data and an interface to graphically navigate this data.
NeoSensory - Condenses decades of neuroscience research into a sleek wristband to deliver hearing solutions that are brand new, simple, and backed by science.
OpenWater - Working on next generation Brain Computer Interfaces.
Blackrock Neurotech - Blackrock Microsystems mission is to provide innovative tools and neurotech expertise to translate technology into novel, implantable clinical solutions that improve human lives.
BCI Society - The purpose of the BCI Society is “to foster research leading to technologies that enable people to interact with the world through brain signals.”
NeurotechX - A non-profit organization whose mission is to facilitate the advancement of neurotechnology by providing key resources and learning opportunities, and by being leaders in local and worldwide technological initiatives.
OpenBCI - Creates open-source tools for biosensing and neuroscience. ‍
Comparison of Artificial Brain Projects - Dated overview of WBE projects.